SENS

Outlined below is comprehensive Stock Exchange News Service (SENS) data for Ascendis Health broken down according to year and date in an easily downloadable format. Please do not hesitate to get in touch with the investor relations contacts should you require any further information.

2024

SENS (ASC) 2024/12/03 Appointment of permanent CFO SENS (ASC) 2024/11/29 2025 AGM Results SENS (ASC) 2024/10/31 Distribution of AGM Notice and availability of IAR SENS (ASC) 2024/10/23 Transfer to General Segment SENS (ASC) 2024/10/04 Audited Annual Financial Statements and No Change Statement SENS (ASC) 2024/09/26 Director’s Dealing and Beneficial interest in Securities SENS (ASC) 2024/09/19 Beneficial interest in Securities SENS (ASC) 2024/09/17 Director’s Dealing SENS (ASC) 2024/09/09 Director’s Dealing SENS (ASC) 2024/09/03 Reviewed Condensed Consolidated Financial Statements SENS (ASC) 2024/08/30 Trading Statement SENS (ASC) 2024/08/07 Appointment of Interim CFO SENS (ASC) 2024/07/19 Lapse of Transaction SENS (ASC) 2024/07/17 Court Order SENS (ASC) 2024/06/19 TRP Ruling SENS (ASC) 2024/05/09 Revised Salient Dates and Times SENS (ASC) 2024/04/23 Results of GM and TRP Announcement SENS (ASC) 2024/03/27 Unaudited Interim Results for the period ended 31 December 2023 SENS (ASC) 2024/03/25 Further Supplementary FIA and Notice of RGM SENS (ASC) 2024/01/17 Supplementary Information and Shareholders’ Meeting Postponement SENS (ASC) 2024/01/19 Presentation Disclosed on Social Media SENS (ASC) 2024/01/02 Directors’ Dealings

2023

SENS (ASC) 2023/12/18 Distribution of Delisting Circular and Notice of General Meeting SENS (ASC) 2023/12/14 Director's Dealing SENS (ASC) 2023/12/07 – Director’s Dealing SENS (ASC) 2023/12/01 – Director’s Dealing SENS (ASC) 2023/11/30 – Results of the 2023 AGM SENS (ASC) 2023/11/27 – Firm Intention Offer Announcement SENS (ASC) 2023/11/08 – Renewal of Cautionary Announcement SENS (ASC) 2023/10/31 – Availability of the 2023 Integrated Annual Report and Notice of AGM SENS (ASC) 2023/10/04 – Surgical Innovations Successful Exit from Business Rescue SENS (ASC) 2023/09/29 –Annual Financial Statements for the year ended 30 June 2023 SENS (ASC) 2023/09/27 – Appointment of Company Secretary SENS (ASC) 2023/09/27 – Cautionary Announcement SENS (ASC) 2023/09/26 – Trading Statement SENS (ASC) 2023/07/04 – Directors’ dealings SENS (ASC) 2023/06/29 – Directors’ dealings SENS (ASC) 2023/06/22 – Directors’ dealings SENS (ASC) 2023/06/15 – Directors’ dealings SENS (ASC) 2023/06/05 – Directors’ dealings SENS (ASC) 2023/05/24 – Director’s dealing SENS (ASC) 2023/05/23 – Director’s dealing SENS (ASC) 2023/05/18 – Director’s dealing SENS (ASC) 2023/05/12 – Surgical Innovations Business Rescue SENS (ASC) 2023/05/10 – Director’s Dealings SENS (ASC) 2023/04/28 – Director’s Dealing SENS (ASC) 2023/04/19 – Director’s Dealing SENS (ASC) 2023/04/14 – Director’s Dealing SENS (ASC) 2023/04/06– Appointment of Auditors SENS (ASC) 2023/04/06 – Director’s Dealing SENS (ASC) 2023/03/27 - Interim Financial Results for the period ended 31 December 2022 SENS (ASC) 2023/03/20– Change of Auditors SENS (ASC) 2023/03/16 – Trading Statement SENS (ASC) 2023/01/06 – Director’s Dealing SENS (ASC) 2023/01/04 – Director’s Dealing

2022

SENS (ASC) 09/12/2022 – Appointment of Chairman SENS (ASC) 05/12/2022 – Director’s Dealing SENS (ASC) 30/11/2022 – Results of Ascendis AGM and Change to the Board of Directors SENS (ASC) 31/10/2022 – Notice of Additional Ordinary Resolution and change in online registration portal SENS (ASC) 31/10/2022 – Closing of Pharma Transaction SENS (ASC) 31/10/2022 – Director’s Dealing SENS (ASC) 28/10/2022 – Financial Director Function SENS (ASC) 28/10/2022 – Director’s Dealing SENS (ASC) 22/10/2022 – Change to the board of directors SENS (ASC) 13/10/2022 – Disposal of Ascendis Pharma – Results of the General Meeting ASC – SENS 05/10/2022 – Disposal of Ascendis Pharma – Austell Pharma competition commission approval SENS (ASC) 29/09/2022 – Director’s Dealing SENS (ASC) 28/09/2022 – Availability of the Integrated Annual Report and Notice of AGM SENS (ASC) 28/09/2022 – Annual Results for the year ended 30 June 2022 ASC – SENS 27/09/2022 – Disposal of Ascendis Pharma – Correction of previously issued financial effects ASC – SENS 26/09/2022 – Trading statement for the year ended 30 June 2022 ASC – SENS 26/09/2022 – Update in respect of the Austell Pharma Disposal ASC – SENS 23/09/2022 – Changes to the Board ASC – SENS 22/09/2022 – Change in Sponsor ASC – SENS 21/09/2022 – Change in Company Secretary ASC – SENS 14/09/2022 – Change in function of directors ASC – SENS 13/09/2022 – Notification in terms of section 3.83(b) of the JSE Listings Requirements and section 122(3)(b) of the Companies Act ASC – SENS 13/09/2022 – Posting of circular in respect of the disposal of Pharma ASC – SENS 09/09/2022 – Notification in terms of section 3.83(b) of the JSE Listings Requirements and section 122(3)(b) of the Companies Act ASC – SENS 05/09/2022 – Dispensation on 60 day rule to dispatch circular ASC – SENS 29/08/2022 – Notification in terms of section 3.83(b) of the JSE Listings Requirements and section 122(3)(b) of the Companies Act ASC – SENS 26/08/2022 – Notification in terms of section 3.83(b) of the JSE Listings Requirements and section 122(3)(b) of the Companies Act ASC – SENS 25/08/2022 – Notification in terms of section 3.83(b) of the JSE Listings Requirements and section 122(3)(b) of the Companies Act ASC – SENS 22/08/2022 – Results of Rights Offer ASC – SENS 03/08/2022 – Rights offer finalisation announcement and distribution of circular ASC – SENS 01/08/2022 – Rights offer declaration announcement ASC – SENS 26/07/2022 – Rights offer announcement ASC – SENS 19/07/2022 – Proposed Austell Pharma Disposal and Withdrawal of Cautionary Announcement ASC – SENS 12/07/2022 – Dispensation on 60 day rule to dispatch the circular, update on disposals and further cautionary announcement ASC – SENS 28/06/2022 – Changes to the Board ASC – SENS 27/06/2022 – Termination of the Medical disposal, withdrawal and renewal of cautionary announcement ASC – SENS 13/06/2022 – Changes in Functions of Directors ASC – SENS 06/06/2022 – Change to the Board of Directors ASC – SENS 01/06/2022 – Update on the Skin Disposal and Dispensation on 60 Day Rule to Dispatch Circular ASC SENS 20/05/2022 - Directors Dealings ASC – SENS 17/05/2022 – Directors’ Dealings ASC – SENS 17/05/2022 – Update on Debt Facilities and Further Cautionary Announcement ASC – SENS 16/05/2022 – Cautionary Announcement ASC – SENS 13/05/2022 – Directors’ Dealings ASC – SENS 11/05/2022 – Results of the SGM, Lender Engagement, Interest Rate Ratchet and Changes to the Board ASC – SENS 03/05/2022 – Voluntary Announcement: Appointment of COO ASC – SENS 03/05/2022 – Update to Skin disposal ASC – SENS 06/04/2022 – Additional Shareholder Demand ASC – SENS 05/04/2022 – Dispensation received on 60 day rule to dispatch the circular ASC – SENS 05/04/2022 – Dealings in Securities by a Director ASC – SENS 31/03/2022 – Notice of Special General Meeting and New Shareholder Demands ASC – SENS 24/03/2022 – Dealings in Securities by a Director ASC – SENS 17/03/2022 – Demand to call a shareholders meeting ASC – SENS 16/03/2022 – Dealings in Securities by a Director ASC – SENS 15/03/2022 – Financial Information of Proposed Disposals and Withdrawal of Cautionary SENS (ASC) 18/02/2022 – Short form announcement – Unaudited interim results for the six months ended 31 December 2021 ASC – SENS 16/02/2022 – Trading statement for the six months ended 31 December 2021 ASC – SENS 01/02/2022 – Proposed Transactions for the Full Recapitalisation of the Company and further cautionary ASC – SENS 13/01/2022 – Transaction Implementation and Changes to the Board ASC – SENS – 06/01/2022 – Market update

2021

ASC – SENS – 30/12/2021 - EXTENSION OF MILESTONE FULFILMENT DATE AND FURTHER CAUTIONARY ASC – SENS – 22/12/2021 – Appointment of CEO, Debt Facilities and Cautionary Announcement ASC – SENS – 21/12/2021 – Market Update on voting pool ASC – SENS – 21/12/2021 – Clarification of Acting CEO ASC – SENS – 20/12/2021 – Results of Annual General Meeting and Changes to composition of Board and Board Committees ASC – SENS – 20/12/2021 – Board Consultation Period ASC – SENS – 20/12/2021 – Notice of Annual General Meeting ASC – SENS – 17/12/2021 - Exercise by Dissenting Shareholder of Appraisal Rights ASC – SENS – 15/12/2021 – Postponement of Annual General Meeting, appointment of Acting CEO and Acting Chairman, Market Update and Renewal of Cautionary Announcement ASC – SENS – 02/12/2021 - Exercise by Dissenting Shareholders of Appraisal Rights SENS (ASC) 24/11/2021 – Renewal of Cautionary Announcement SENS (ASC) 18/11/2021 – Revised Notice of Annual General Meeting SENS (ASC) 12/11/2021 – Market update SENS (ASC) 11/11/2021 – Notification in terms of section 3.83(b) of the JSE Listings Requirements and section 122(3)(b) of the Companies Act SENS (ASC) 05/11/2021 – Board changes SENS (ASC) 29/10/2021 – Notice of AGM and No Change Statement Announcement SENS (ASC) 28/10/2021 – Notification in terms of section 3.83(b) of the JSE Listings Requirements and section 122(3)(b) of the Companies Act SENS (ASC) 22/10/2021 – Change to the board of directors SENS (ASC) 21/10/2021 – Change to the board of directors SENS (ASC) 21/10/2021 – Group Recapitalisation Closing SENS (ASC) 19/10/2021 – Market update “SENS (ASC) 13/10/2021 – Cautionary Announcement SENS (ASC) 04/10/2021 – Results of the General Meeting SENS (ASC) 30/09/2021 – Annual Results for the year ended 30 June 2021 Revised trading statements for the year ended 30 June 2021 SENS (ASC) 20/09/2021 – Strategy and Operational Update and Trading Statement for the year ended 30 June 2021 SENS (ASC) 06/09/2021 – Market Update on recent speculation in respect of a potential offer to Ascendis Health Shareholders SENS (ASC) 03/09/2021 – Market Update SENS (ASC) 03/09/2021 – Announcement regarding the posting of the Recapitalisation Circular and Notice convening the General Meeting SENS (ASC) 30/08/2021 – Announcement regarding the Group Recapitalisation and withdrawal of Cautionary Announcement SENS (ASC) 04/08/2021 – Clarification regarding dispensation received on 60-day rule to dispatch RCA circular and Renewal of Cautionary Announcement SENS (ASC) 23/07/2021 – Dispensation received on 60 day rule to dispatch circular SENS (ASC) 19/07/2021 – Notification in terms of section 3.83(b) of the JSE Listings Requirements and section 122(3) of the Companies Act SENS (ASC) 19/07/2021 – Proposed Disposal of the Ascendis Animal health Division SENS (ASC) 09/07/2021 – Market Update SENS (ASC) 25/06/2021 – Proposed disposal of Farmalider SENS (ASC) 23/06/2021 – Market update and Renewal of Cautionary Announcement SENS (ASC) 26/05/2021 – Category 1 Transaction Announcement Relating to the Proposed Disposal of RCA SENS (ASC) 12/05/2021 – Announcement relating to the proposed disposal of the Biosciences business SENS (ASC) 12/05/2021 – Investor presentation on Group Recapitalisation SENS (ASC) 12/05/2021 – Proposed transaction for the Recapitalisation of Ascendis Health and further cautionary announcement. SENS (ASC) 30/04/2021 – Market Update SENS (ASC) 26/04/2021 – Renewal of cautionary announcement SENS (ASC) 07/04/2021 – Notification in terms of section 3.83(b) of the JSE Listings Requirements and section 122(3) of the Companies Act SENS (ASC) 31/03/2021 – Short form announcement – Unaudited interim results for the six months ended 31 December 2020 SENS (ASC) 25/03/2021 – Trading statement for the six months ended 31 December 2020 SENS (ASC) 10/03/2021 – Market Update and Cautionary SENS (ASC) 04/03/2021 – Change to the board of directors SENS (ASC) 09/02/2021 – Disclosure of change in significant holding of Ascendis Health ordinary shares SENS (ASC) 04/02/2021 – Disclosure of change in significant holding of Ascendis Health ordinary shares SENS (ASC) 02/02/2021 – Market Update SENS (ASC) 25/01/2021 – Market Update SENS (ASC) 15/01/2021 – The promotion of Ivermax 1% to treat COVID-19 on social media

2020

SENS (ASC) 01/12/2020 – Results of Eighth Annual General Meeting SENS (ASC) 01/12/2020 – Voluntary business update SENS (ASC) 29/10/2020 – Availability of 2020 Integrated Annual Report, Audited Group Annual Financial Statements for the year ended 30 June 2020, No Change Statement and distribution of Notice of Annual General Meeting SENS (ASC) 29/10/2020 – Changes to Board Committees SENS (ASC) 14/10/2020 – Change to the board of directors SENS (ASC) 13/10/2020 – Appointment of Chief Financial Officer SENS (ASC) 09/10/2020 Notification of B-BBEE certificate for 2020 SENS (ASC) 30/09/2020 – Corrected announcement: Condensed consolidated financial results for the year ended 30 June 2020 SENS (ASC) 22/09/2020 – Trading statement for year ended 30 June 2020 SENS (ASC) 21/09/2020 – Disposals of Dezzo Trading and Ascendis Direct Selling SENS (ASC) 31/07/2020 – Fulfilment of conditions precedent to the disposal of the Scitec business SENS (ASC) 23/06/2020 – Change in Company Secretary SENS (ASC) 18/06/2020 – Media coverage relating to drugs in the treatment of patients with COVID-19 SENS (ASC) 10/06/2020 – Resignation of Chief Financial Officer SENS (ASC) 08/06/2020 – Restructure and extension of Debt Facilities SENS (ASC) 15/05/2020 – Extension of ISA Period SENS (ASC) 16/04/2020 – Proposed Disposal of Scitec SENS (ASC) 15/04/2020 – Dealings in securities by a director SENS (ASC) 14/04/2020 – Dealings in securities by a director SENS (ASC) 08/04/2020 – Change to the Board of Directors SENS (ASC) 08/04/2020 – Voluntary update relating to the impact of COVID-19 on the Ascendis Health operations SENS (ASC) 11/03/2020 – Short form announcement – Unaudited condensed consolidated financial results for the six months ended 31 December 2019 SENS (ASC) 05/03/2020 – Trading statement for the six months ended 31 December 2019 SENS (ASC) 05/02/2020 – Results of Seventh Annual General Meeting SENS (ASC) 05/02/2020 – Voluntary Trading Update for the Six Months ended 31 December 2019 SENS (ASC) 30/01/2020 – Market Update

2019

SENS (ASC) 30/12/2019 – Dealings in securities by a director SENS (ASC) 20/12/2019 – Trading Update SENS (ASC) 17/12/2019 – Withdrawal of cautionary announcement SENS (ASC) 03/12/2019 – Further cautionary announcement SENS (ASC) 08/11/2019 – Disclosure of beneficial interests SENS (ASC) 31/10/2019 – Distribution of integrated annual report and notice of annual general meeting SENS (ASC) 30/10/2019 – Annual Results for the year ended 30 June 2019 SENS (ASC) 22/10/2019 – Trading statement for the year ended 30 June 2019 and renewal of cautionary announcement SENS (ASC) 14/10/2019 – Director’s Dealings – Acceptance of Executive Option Agreement SENS (ASC) 02/10/2019 – Rescheduling of release of annual results and renewal of cautionary announcement SENS (ASC) 25/09/2019 – Postponement of release of annual results SENS (ASC) 19/09/2019 – Notification of B-BBEE certificate for 2019 SENS (ASC) 03/09/2019 – Further cautionary announcement SENS (ASC) 02/09/2019 – Appointment of Chief Executive Officer and Executive Director SENS (ASC) 31/07/2019 – Disposal of Afrikelp, Efekto and Marltons businesses within the Ascendis Health Biosciences division: Transaction unconditional SENS (ASC) 22/07/2019 – Further cautionary announcement SENS (ASC) 07/06/2019 – Change in director’s responsibilities, change to the board and renewal of cautionary announcement SENS (ASC) 23/05/2019 – Change to the Board SENS (ASC) 10/05/2019 – Disposal of a beneficial interest in Ascendis Health SENS (ASC) 06/05/2019 – Correction to published NAV in Biosciences disposal announcement SENS (ASC) 03/05/2019 – Changes to the Board of Directors SENS (ASC) 02/05/2019 – Disposal of Afrikelp, Efekto and Marltons businesses within the Ascendis Biosciences division SENS (ASC) 25/04/2019 – Notification of changes proposed to the Board SENS (ASC) 24/04/2019 – Further cautionary announcement SENS (ASC) 01/04/2019 – Dealings in Securities by Directors SENS (ASC) 29/03/2019 – Dealings in Securities by Directors SENS (ASC) 26/03/2019 – Change to the Board – Resignation of Director SENS (ASC) 25/03/2019 – Dealings in Securities by Directors SENS (ASC) 18/03/2019 – Unaudited condensed consolidated interim results for the six months ended 31st December 2018 SENS (ASC) 15/03/2019 – Further information in respect of restatement disclosed in Trading Statement SENS (ASC) 13/03/2019 – Dealings in Securities by Directors SENS (ASC) 08/03/2019 – Voluntary trading statement for the six months ended 31 December 2018, update on strategic divestments and further cautionary announcement SENS (ASC) 28/02/2019 – Dealings in Securities by Directors SENS (ASC) 22/02/2019 – Dealings in Securities by Directors SENS (ASC) 19/02/2019 – Dealings in Securities by Directors SENS (ASC) 13/02/2019 – s.122 Beneficial Ownership – Mergence Investments SENS (ASC) 08/02/2019 – Dealings in Securities by Directors SENS (ASC) 08/02/2019 – Cautionary Announcement SENS (ASC) 06/02/2019 – s.122 Beneficial Ownership – Legae Peresec (Pty) Ltd SENS (ASC) 04/02/2019 – Dealings in Securities by Directors SENS (ASC) 29/01/2019 – Dealings in Securities by Directors SENS (ASC) 18/01/2019 – Dealings in Securities by Directors SENS (ASC) 15/01/2019 – Dealings in Securities by Directors SENS (ASC) 14/01/2019 – Cautionary Announcement SENS (ASC) 09/01/2019 – Dealings in Securities by Directors SENS (ASC) 03/01/2019 – Dealings in Securities by Directors

2018

SENS (ASC) 24/12/2018 – Dealings in Securities by Directors SENS (ASC) 20/12/2018 – Conclusion of a Sale Agreement in respect of the Isando Manufacturing Facility SENS (ASC) 18/12/2018 – Dealings in Securities by Directors SENS (ASC) 11/12/2018 – Dealings in Securities by Directors SENS (ASC) 05/12/2018 – Dealings in Securities by Directors SENS (ASC) 28/11/2018 – Dealings in Securities by Directors SENS (ASC) 22/11/2018 – Dealings in Securities by Directors SENS (ASC) 16/11/2018 – Dealings in Securities by Directors SENS (ASC) 13/11/2018 – Dealings in Securities by Directors SENS (ASC) 09/11/2018 – Results of Sixth Annual General Meeting SENS (ASC) 02/11/2018 – Dealings in Securities by Directors SENS (ASC) 26/10/2018 – Dealings in Securities by Directors SENS (ASC) 24/10/2018 – Dealings in Securities by Directors SENS (ASC) 23/10/2018 – Dealings in Securities by Directors SENS (ASC) 22/10/2018 – Dealings in Securities by Directors SENS (ASC) 12/10/2018 – Availability of Broad-Based Black Economic Empowerment Annual Compliance Report SENS (ASC) 03/10/2018 – Posting of Integrated Annual Report, No Change Statement and Notice of Annual General Meeting SENS (ASC) 02/10/2018 – Change to the Board SENS (ASC) 25/09/2018 – Ascendis Health adopts new Strategy Focus SENS (ASC) 25/09/2018 – Annual Results for the year ended 30 June 2018 SENS (ASC) 07/09/2018 – Voluntary trading Statement on expected financial results for year ending 30 June 2018 SENS (ASC) 25/06/2018 – Investor Update on Strategic Business Review and Change in Directors SENS (ASC) 22/05/2018 – Secondary Listing on A2X SENS (ASC) 11/05/2018 – Dealings in Securities by Directors SENS (ASC) 10/05/2018 – Dealings in Securities by Directors SENS (ASC) 18/04/2018 – Notification of a change in indirect beneficial interests of directors SENS (ASC) 09/04/2018 – Dealings in Securities by Directors SENS (ASC) 04/04/2018 – Dealings in Securities by Directors SENS (ASC) 26/03/2018 – Dealings in Securities by Directors SENS (ASC) 06/03/2018 – Dealings in Securities by Directors SENS (ASC) 01/03/2018 – Unaudited condensed consolidated interim results for the six months ended 31st December 2017 SENS (ASC) 27/02/2018 – Appointment of new Chief Executive Officer SENS (ASC) 01/02/2018 – Clarification Note on Voluntary Trading Statement SENS (ASC) 31/01/2018 – Voluntary Trading Statement on expected financial results for six month period ending 31st December 2017 SENS (ASC) 22/01/2018 – s.122 Beneficial Ownership – WDB Investment Holdings (Pty) Ltd & Sentio Capital Management (Pty) Ltd SENS (ASC) 19/01/2018 – Change in Sponsor SENS (ASC) 02/01/2018 – Dealings in Securities by Directors

2017

SENS (ASC) 29/12/2017 – Dealings in Securities by Directors SENS (ASC) 22/12/2017 – Dealings in Securities by Directors SENS (ASC) 20/12/2017 – s.122 Beneficial Ownership – Coast2coast Capital (Pty) Ltd SENS (ASC) 20/12/2017 – Dealings in Securities by Directors SENS (ASC) 18/12/2017 – Dealings in Securities by Directors SENS (ASC) 18/12/2017 – Results of the Rights Offer SENS (ASC) 14/12/2017 – Dealings in Securities by Directors SENS (ASC) 12/12/2017 – Dealings in Securities by Directors SENS (ASC) 11/12/2017 – advisement of updated B-BBEE certificate for 2017 SENS (ASC) 11/12/2017 – Dealings in Securities by Directors SENS (ASC) 08/12/2017 – Dealings in Securities by Directors SENS (ASC) 07/12/2017 – Dealings in Securities by Directors SENS (ASC) 05/12/2017 – Dealings in Securities by Directors SENS (ASC) 04/12/2017 – Dealings in Securities by Directors SENS (ASC) 01/12/2017 – Dealings in Securities by Directors SENS (ASC) 30/11/2017 – Dealings in Securities by Directors SENS (ASC) 28/11/2017 – Voluntary announcement: Acquisition of 100% of Kyron Laboratories Proprietary Limited SENS (ASC) 23/11/2017 – Finalisation announcement relating to fully underwritten renounceable rights offer SENS (ASC) 21/11/2017 – Declaration announcement relating to a fully underwritten renounceable rights offer of R750 million at R20.00 per share SENS (ASC) 13/11/2017 – Transaction update relating to Ascendis’ acquisition of Remedica SENS (ASC) 10/11/2017 – Report on Fifth Annual General Meeting Proceedings SENS (ASC) 01/11/2017 – Voluntary Announcement: Proposed Rights Offer SENS (ASC) 31/10/2017 – Change to Board of Directors: Retirement of MD of South Africa operations on 30 June 2018 SENS (ASC) 16/10/2017 – advisement of B-BBEE certificate for 2017 SENS (ASC) 29/09/2017 – IAR2017 & No Change Statement & Notice to fifth AGM SENS (ASC) 29/09/2017 - Dealings in Securities by Non-executive Directors SENS (ASC) 12/09/2017 – Annual Results for the year ended 30 June 2017 SENS (ASC) 31/08/2017 – Appointment of Chief Operating Officer of Ascendis SENS (ASC) 24/08/2017 – Trading Statement on expected results for year ending 30 June 2017 SENS (ASC) 13/06/2017 – Dealings in Securities by Executive Director SENS (ASC) 12/06/2017 – Pre Closed Period Briefing SENS (ASC) 07/06/2017 – Dealings in Securities by Executive Director SENS (ASC) 02/06/2017 – Fulfilment of all outstanding Conditions Precedent relating to Acquisition of Assets of Sunwave Pharma and NHP Pharma SENS (ASC) 01/06/2017 – Fulfilment of all outstanding Conditions Precedent relating to Acquisitions of Cipla Agrimed and Cipla Vet SENS (ASC) 12/05/2017 - Dealings in Securities by an Associate of a Non-executive Director SENS (ASC) 25/04/2017 - Dealings in Securities by Non-executive Directors SENS (ASC) 13/03/2017 - Dealings in Securities by Non-executive Directors SENS (ASC) 08/03/2017 – Unaudited condensed consolidated interim results for the six months ended 31st December 2016 SENS (ASC) 07/03/2017 - Acquisition of assets of Sunwave Pharma SRL and NHP Pharma Ltd SENS (ASC) 06/03/2017 – Acquisition of 100% of Cipla Agrimed Proprietary Limited and Cipla Vet Proprietary Limited SENS (ASC) 23/02/2017 – Trading Statement on expected financial results for six month period ending 31st December 2016

2016

SENS (ASC) 15/12/2016 - Dealings in Securities by Non-executive Directors SENS (ASC) 11/11/2016 – Report on Fourth Annual General Meeting Proceedings SENS (ASC) 11/11/2016 – s.122 Beneficial Ownership – Coast2Coast Holdings (Pty) Ltd SENS (ASC) 01/11/2016 - Dealings in Securities by Non-executive Directors SENS (ASC) 12/10/2016 – No Change Statement & Notice to Fourth AGM & IAR 2016 SENS (ASC) 03/10/2016 - Dealings in Securities by Non-executive Director SENS (ASC) 14/09/16 – Annual Results for the year ended 30 June 2016 SENS (ASC) 07/09/2016 – Trading Statement on expected results for year ending 30 June 2016 SENS (ASC) 30/08/2016 – s.122 Beneficial Ownership – Kefolile Health Investments (Pty) Ltd SENS (ASC) 26/08/2016 – Fulfilment of all outstanding Conditions Precedent relating to the Acquisitions of Remedica and Scitec SENS (ASC) 15/08/2016 – s.122 Beneficial Ownership – Coast2Coast Holdings (Pty) Ltd SENS (ASC) 11/08/2016 – Results of the General Meeting and Update on Equity Raise SENS (ASC) 08/08/2016 – Dealings in Securities by Directors and Company Secretary SENS (ASC) 08/08/2016 – Results of the Rights Offer SENS (ASC) 05/08/2016 – Director’s Dealings SENS (ASC) 21/07/2016 – Amendment to circular re treatment of fractional entitlements SENS (ASC) 12/07/2016 – Rights offer of R1.2b; Circular posting; Notice of General Meeting SENS (ASC) 30/06/2016 – Rights Offer Declaration SENS (ASC) 30/06/2016 – Dealings in Securities by Non-executive directors SENS (ASC) 10/06/2016 – General Issue of Shares for Cash SENS (ASC) 03/06/2016 – Dealings in Securities by Non-executive Directors SENS (ASC) 03/06/2016 – Dealings in Securities by Non-executive Director SENS (ASC) 25/05/2016 – Director’s Associate Dealings SENS (ASC) 24/05/2016 – Acquisition of Remedica Holdings Limited and Scitec International Societe A Responsabilite Limitee and Withdrawal of Cautionary Announcement SENS (ASC) 19/04/2016 – Dealings in Securities by Non-executive Directors SENS (ASC) 13/04/2016 – Akacia Healthcare Holdings fulfilment of conditions SENS (ASC) 14/03/2016 – Cautionary announcement SENS (ASC) 10/03/2016 – Dealings in Securities by Non-executive Directors SENS (ASC) 09/03/2016 – Unaudited condensed consolidated interim results for the six months ended 31 December 2015 SENS(ASC) 02/03/2016 – Trading Statement on expected financial results for six month period ending 31st December 2015

2015

“SENS (ASC) 17/12/2015 – Dealings in Securities by Non-executive Directors SENS (ASC) 15/12/2015 – Directors’ Dealings SENS (ASC) 08/12/2015 – Dealings in Securities by Non-executive Directors SENS (ASC) 02/12/2015 – Dealings in Securities by Non-executive Directors SENS (ASC) 19/11/2015 – Dealings in Securities by Non-executive Directors SENS (ASC) 19/11/2015 – Acquisition of Akacia Healthcare Holdings Proprietary Limited SENS (ASC) 13/11/2015 – Report on Third Annual General Meeting Proceedings SENS (ASC) 22/10/2015 – Dealings in Securities by Non-executive Directors SENS (ASC) 14/10/2015 – No Change Statement & Notice to Third AGM & IAR 2015 SENS (ASC) 25/09/2015 – Director’s Dealings SENS (ASC) 09/09/2015 – Annual Results for the year ended 30 June 2015 SENS (ASC) 01/09/2015 – Trading Statement on expected results for year ending 30 June 2015 SENS (ASC) 27/08/2015 – Appointment of executive director and CFO of Ascendis SENS (ASC) 27/08/2015 – s.122 Beneficial Ownership – Investec Ltd SENS (ASC) 14/08/2015 – Dealings in securities by directors and notification in terms of Section 122(3) of the Companies Act and Section 3.83(b) of the JSE Listings Requirements ENS (ASC) 05/08/2015 – Acquisition Of Initial 49% Of Farmalider S.A. SENS (ASC) 02/07/2015 – s.122 Beneficial Ownership – Investec Ltd SENS (ASC) 30/06/2015 – s.122 Beneficial Ownership – Coast2Coast Holdings (Pty) Ltd SENS (ASC) 29/06/2015 – Dealings in Securities by Non-executive Directors SENS (ASC) 26/06/2015 – Director’s Dealings SENS (ASC) 25/06/2015 – Share Dealings in Securities by Acting Managing Director SENS (ASC) 09/06/2015 – Proposed appointment of executive director of Ascendis SENS (ASC) 22/05/2015 – Dealings in Securities by Non-executive Directors SENS (ASC) 24/04/2015 – Resignation of Chief Financial Officer SENS (ASC) 07/04/2015 – s.122 Beneficial Ownership – Investec Ltd SENS (ASC) 01/04/2015 – Dealings in Securities by Non-executive Directors SENS (ASC) 25/03/2015 – Dealings in Securities by Non-Executive Directors SENS (ASC) 11/03/2015 – Unaudited condensed consolidated interim results for the six months ended 31 December 2014 SENS (ASC) 06/03/2015 – Trading Statement on expected financial results for six month period ending 31st December 2014 SENS (ASC) 02/03/2015 – Scientific Group fulfillment of conditions

2014

SENS (ASC) 11/12/2014 – s.122 Benefical Ownership – Investec Ltd SENS (ASC) 27/11/2014 – Directors Dealings SENS (ASC) 26/11/2014 – WDB and Senatla Capital BEE Announcement SENS (ASC) 25/11/2014 – s.122 Beneficial Ownership – Coast2Coast Holdings (Pty) Ltd SENS (ASC) 18/11/2014 – s.122 Benefical Ownership – Investec Ltd SENS (ASC) 14/11/2014 – Report on Second Annual General Meeting Proceedings SENS (ASC) 07/11/2014 – Directors’ dealings SENS (ASC) 07/11/2014 – Private placement of shares SENS (ASC) 04/11/2014 – Share Dealings in Securities by Director SENS (ASC) 27/10/2014 – Acquisition Of The Majority Of The Scientific Group Proprietary Limited (“SG”) SENS (ASC) 16/10/2014 – No Change Statement & Notice of AGM 2014 SENS (ASC) 06/10/2014 – Dealings in Securities by Non-Executive Directors SENS (ASC) 29/09/2014 – Ascendis To Refinance Existing Debt SENS (ASC) 25/09/2014 – Directors dealings in securities SENS (ASC) 15/09/2014 – Announcement regarding WDB Investment Holdings Proprietary Limited SENS (ASC) 12/09/2014 – Director’s Associate Dealings SENS (ASC) 09/09/2014 – Annual Results for the year ended 30 June 2014 SENS (ASC) 02/09/2014 – Voluntary Trading Update on expected financial results for June 2014 SENS (ASC) 25/08/2014 – Fulfilment Of Outstanding Conditions Precedent Regarding The Acquisition By Ascendis Of Respiratory Care Africa Proprietary Limited SENS (ASC) 11/08/2014 – Acquisition Of Leading Products From Arctic Healthcare Proprietary Limited SENS (ASC) 26/06/2014 – BBBEE Announcement ENS (ASC) 26/06/2014 – Dealings in Securities by Non-Executive Directors SENS (ASC) 12/06/2014 – Acquisition of Respiratory Care Africa Proprietary Limited SENS (ASC) 11/06/2014 – Complementary Medicines effect on Ascendis – Correction SENS (ASC) 02/06/2014 – Pharma Natura fulfilment of conditions precedent SENS (ASC) 23/05/2014 – Dealings in securities by directors SENS (ASC) 29/04/2014 – Appointment of Sponsor SENS (ASC) 28/03/2014 – Change of Sponsor SENS (ASC) 06/03/2014 – Dealings in securities by directors SENS (ASC) 03/03/2014 – Changes To Company Secretary SENS (ASC) 03/03/2014 – Unaudited condensed consolidated interim results for the six months ended 31 December 2013 SENS (ASC) 27/01/2014 – Acquisition of Pharma Natura Proprietary Limited (“Pharma Natura”) SENS (ASC) 21/01/2014 – Fulfilment of outstanding condition precedent

2013

SENS (ASC) 17/12/2013 – Directors Dealings SENS (ASC) 02/12/2013 – Directors Dealings SENS (ASC) 25/11/2013 – Acquisition of Surgical Innovations and Withdrawal of Cautionary Announcement SENS (ASC) 22/11/2013 – Cautionary Announcement SENS (ASC) 15/11/2013 – Abridged Pre-listing Statement